Effective Topical Agents and Emerging Perspectives in the Treatment of Psoriasis

Andrea Chiricozzi; Sergio Chimenti
Expert Rev Dermatol. 2012;7(3):283-293. © 2012 Expert Reviews Ltd.

Psoriasis is one of the most common inflammatory skin diseases. The mild form of psoriasis is usually treated with topical medications and phototherapy, whereas conventional systemic therapies, including retinoids, cyclosporine and methotrexate, are used for the treatment of moderate-to-severe psoriasis. The therapeutic approach has been revolutionized over the past decade by the introduction of biologic agents or 'small molecules' that have been proven to have striking clinical efficacy. This review highlights the most effective topical antipsoriatic treatments, focusing on emerging promising topical drugs that are currently being tested in ongoing clinical trials.

PDF is attached at the bottom of this page

PDF Table of Contents

Abstract and Introduction
Psoriasis as a Complex Immune-mediated Disorder
Conventional Topical Agents
Corticosteroids
Vitamin D3 Derivatives
Combined Therapy With Vitamin D3 Derivatives & Corticosteroids
Retinoids
Tars & Anthralin
Keratolytics
Topical Calcineurin Inhibitors
New Perspectives for Topical Therapy
MEK1/MEKK1 Inhibitor
Other Nonsteroidal Anti-inflammatory Agents
Expert Commentary
Five-year View
References
Sidebar
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See also VitaminDWiki

• All items in category Psoriasis and Vitamin D 72 items
• Psoriasis, metabolic syndrome, and vitamin D – 2011
• Psoriasis best treated by combinations such as vitamin D and UVB – meta-analysis Dec 2011
• Psorasis combination therapies usually include vitamin D – review Feb 2013

See also web

• Psoriasis random controlled trial starting in NZ in 2012
  100,000 IU vitamin D monthly for a year ( 3,300 IU daily, probably not enough)